- Symbol
- Pink1
- Name
- PTEN-induced putative kinase 1
- Organism
- Drosophila melanogaster (AnAge)
- Observations
- Transgenic overexpression of Pink1 results in an increase in mean lifespan (18%) mean = 72 days) when compared to wild-type controls. This effect is enhanced even more (up to 41%) when alpha-synuclein is also overexpressed. In both cases, lifespan extension is accompanied by an increase in healthspan.
- % change in avg or median lifespan
- Mean lifespan is 18% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- CellAge
- A homolog of this gene for Homo sapiens is present as PINK1
- CellAge gene expression
- A homolog of this gene for Homo sapiens is present as PINK1
- Caenorhabditis elegans
- pink-1
- Danio rerio
- pink1
- Homo sapiens
- PINK1
- Mus musculus
- Pink1
- Rattus norvegicus
- Pink1
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (31607)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Pink1 (Drosophila melanogaster)