Drosophila melanogasterGenAge entry for NLaz (Drosophila melanogaster)

Gene information (ID: 872)

Symbol
NLaz
Aliases
BcDNA:RE67583; CG16933; CG33126; CT33980; Dmel\CG33126
Name
Neural Lazarillo
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Absence of Nlaz, an homologue of ApoD, leads to reduced lifespan in both sexes compared to wild type flies.
% change in max lifespan
Maximum female lifespan is approximately 12% lower; Maximum male lifespan is approximately 30% lower.
% change in avg or median lifespan
Median female lifespan is 30.8% lower; Median male lifespan is 22.5% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutations
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge microarray genes
    • A homolog of this gene for Homo sapiens is present as APOD

    Homologs in other organisms

    Danio rerio
    apoda.2
    Danio rerio
    apoda.1
    Danio rerio
    apodb
    Homo sapiens
    APOD
    Mus musculus
    Apod
    Rattus norvegicus
    Apod

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (33324)
    Homologues
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    UniProt
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    Internet
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