Mus musculusGenAge entry for Mstn (Mus musculus)

Gene information (ID: 2080)

Symbol
Mstn
Name
myostatin
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Mstn+/- and Mstn-/- mice were protected from age-related decline in muscle mass and contractility. MSTN+/- mice demonstrated a 15% increase in maximal lifespan when compared to Mstn+/+ and Mstn-/- mice.
% change in max lifespan
Maximum lifespan is 15% higher
% change in avg or median lifespan
15%
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Drosophila melanogaster is present as myo
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as MSTN

    Homologs in other organisms

    Danio rerio
    mstnb
    Danio rerio
    mstna
    Drosophila melanogaster
    myo
    Homo sapiens
    MSTN
    Rattus norvegicus
    Mstn

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (17700)
    Homologues
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    UniProt
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    Internet
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