- Symbol
- Mnt
- Aliases
- bHLHe43; CG13316; CG2856; dMad; Dmel\CG13316; DmMnt; dmn
- Name
- CG13316-PC, isoform C
- Organism
- Drosophila melanogaster (AnAge)
- Known functions and activities
- Homolog of the mammalian Mnt and Mad family of transcriptional repressors
- Observations
- Mnt overexpression in flies lowers climbing defects and increases both median and maximum lifespan.
- % change in max lifespan
- Maximum lifespan is aproximately 20% higher.
- % change in avg or median lifespan
- Median lifespan is aproximately 35% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- A dMnt null allele results in flies with larger cells, increased weight, and decreased lifespan.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Knockout
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Danio rerio
- MNT (1 of many)
- Danio rerio
- mntb
- Homo sapiens
- MNT
- Mus musculus
- Mnt
- Rattus norvegicus
- Mnt
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (31331)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Mnt (Drosophila melanogaster)