GenAge entry for Mir17 (Mus musculus)
Gene information (ID: 2171)
- Symbol
- Mir17
- Name
- microRNA 17
- Organism
- Mus musculus (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- Mice overexpressing miR-17 demonstrated a 16% increase in lifespan compared to wild type mice. Mice overexpressing miR-17 had increased bone mass and reduced cell senescence. However, mice overexpressing miR-17 also developed liver tumours.
- % change in avg or median lifespan
- Median lifespan is 16% higher
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
Homologs in other organisms
No homologs found
External links
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (723905)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar