Mus musculusGenAge entry for Mir17 (Mus musculus)

Gene information (ID: 2171)

Symbol
Mir17
Name
microRNA 17
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Mice overexpressing miR-17 demonstrated a 16% increase in lifespan compared to wild type mice. Mice overexpressing miR-17 had increased bone mass and reduced cell senescence. However, mice overexpressing miR-17 also developed liver tumours.
% change in avg or median lifespan
Median lifespan is 16% higher
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    No homologs found

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (723905)
    Homologues
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    UniProt
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    Internet
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