Saccharomyces cerevisiaeGenAge entry for MPD1 (Saccharomyces cerevisiae)

Gene information (ID: 1864)

Symbol
MPD1
Name
protein disulfide isomerase MPD1
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Deletion of mpd1, a target of the unfolded protein response signaling, increases replicative lifespan.
% change in avg or median lifespan
Mean lifespan is 17% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    pdi-6
    Caenorhabditis elegans
    Y73B6BL.12
    Caenorhabditis elegans
    dnj-27
    Caenorhabditis elegans
    Y49E10.4
    Danio rerio
    pdia6
    Danio rerio
    pdia5
    Danio rerio
    txndc5
    Danio rerio
    dnajc10
    Drosophila melanogaster
    CG9302
    Drosophila melanogaster
    prtp
    Drosophila melanogaster
    CaBP1
    Homo sapiens
    PDIA6
    Homo sapiens
    PDIA5
    Homo sapiens
    TXNDC5
    Homo sapiens
    DNAJC10
    Mus musculus
    Pdia6
    Mus musculus
    Txndc5
    Mus musculus
    Dnajc10
    Mus musculus
    Pdia5
    Rattus norvegicus
    Txndc5
    Rattus norvegicus
    LOC685171
    Rattus norvegicus
    Pdia6
    Rattus norvegicus
    Dnajc10
    Rattus norvegicus
    Pdia5
    Schizosaccharomyces pombe
    SPAC13F5.05

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (854462)
    Homologues
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    UniProt
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    Internet
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