Caenorhabditis elegansGenAge entry for M57.2 (Caenorhabditis elegans)

Gene information (ID: 423)

Symbol
M57.2
Name
Protein M57.2
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Geranylgeranyl transferase

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 20% in wild type animals and 40% in daf-2 mutants.
% change in avg or median lifespan
Median lifespan is 20% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    rabggta
    Drosophila melanogaster
    CG12007
    Homo sapiens
    RABGGTA
    Mus musculus
    Rabggta
    Rattus norvegicus
    Rabggta
    Saccharomyces cerevisiae
    BET4

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (177113)
    Homologues
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    UniProt
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    Internet
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