Drosophila melanogasterGenAge entry for Keap1 (Drosophila melanogaster)

Gene information (ID: 859)

Symbol
Keap1
Aliases
CG3962; dkeap1; dKeap1; dKEAP1; Dmel\CG3962; keap1; KEAP
Name
CG3962 gene product from transcript CG3962-RA
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Male keap1 heterozygotes lived significantly longer than their otherwise genetically identical siblings. Female keap1 heterozygotes did not show significant differences in either paraquat resistance or longevity.
% change in avg or median lifespan
Median male lifespan was 8%-10% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutations
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    CellAge
    • A homolog of this gene for Homo sapiens is present as KEAP1

    Homologs in other organisms

    Danio rerio
    keap1a
    Danio rerio
    keap1b
    Homo sapiens
    KEAP1
    Mus musculus
    Keap1
    Rattus norvegicus
    Keap1

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (42062)
    Homologues
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    UniProt
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    Internet
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