- Symbol
- Ikbkb
- Aliases
- IKK2; IKK-2; IKK[b]; IKKbeta; AI132552; IKK-beta
- Name
- inhibitor of kappaB kinase beta
- Organism
- Mus musculus (AnAge)
- Observations
- Brain-specific knockout mice live 23% longer. Moreover, viral activation in the hypothalamus activated NFkB and reduced lifespan.
- % change in avg or median lifespan
- Average lifespan is 23% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Knockout
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as ATG1
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as IKBKB
- GenDR gene manipulations
- A homolog of this gene for Saccharomyces cerevisiae is present as ATG1
- Caenorhabditis elegans
- T07F12.4
- Danio rerio
- ikbkb
- Drosophila melanogaster
- ird5
- Homo sapiens
- IKBKB
- Rattus norvegicus
- Ikbkb
- Saccharomyces cerevisiae
- ATG1
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (16150)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Ikbkb (Mus musculus)