Drosophila melanogasterGenAge entry for Hex-A (Drosophila melanogaster)

Gene information (ID: 2150)

Symbol
Hex-A
Name
Hexokinase A
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
A mutation that decreased Hex-A activity in flies increased lifespan by 10%.
% change in avg or median lifespan
Mean lifespan is 10% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as HXK2
    • A homolog of this gene for Saccharomyces cerevisiae is present as GLK1
    GenDR gene expression
    • A homolog of this gene for Mus musculus is present as Gck
    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as HXK2
    CellAge
    • A homolog of this gene for Homo sapiens is present as HK3

    Homologs in other organisms

    Caenorhabditis elegans
    hxk-1
    Danio rerio
    gck
    Danio rerio
    hkdc1
    Danio rerio
    hk2
    Danio rerio
    hk1
    Homo sapiens
    HK2
    Homo sapiens
    GCK
    Homo sapiens
    HK1
    Homo sapiens
    HKDC1
    Homo sapiens
    HK3
    Mus musculus
    Hk2
    Mus musculus
    Hkdc1
    Mus musculus
    Hk1
    Mus musculus
    Hk3
    Mus musculus
    Gck
    Rattus norvegicus
    Hk3
    Rattus norvegicus
    Gck
    Rattus norvegicus
    LOC100364027
    Rattus norvegicus
    Hk2
    Rattus norvegicus
    Hk1
    Saccharomyces cerevisiae
    HXK2
    Saccharomyces cerevisiae
    GLK1

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (45875)
    Homologues
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    UniProt
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    Internet
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