Mus musculusGenAge entry for Grn (Mus musculus)

Gene information (ID: 1814)

Symbol
Grn
Aliases
epithelin
Name
granulin
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Knockout mice exhibited decreased survival, with less than 50% of animals living more than 2 years, and signs of cellular ageing, though not necessarily progeroid features.
Lifespan Effect
Decrease
Genetic Manipulation
Knockout
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as GRN
    GenAge microarray genes
    • A homolog of this gene for Homo sapiens is present as GRN
    CellAge
    • A homolog of this gene for Homo sapiens is present as GRN
    CellAge gene expression
    • A homolog of this gene for Homo sapiens is present as GRN

    Homologs in other organisms

    Caenorhabditis elegans
    pgrn-1
    Danio rerio
    grna
    Danio rerio
    grnb
    Homo sapiens
    GRN
    Rattus norvegicus
    Grn

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (14824)
    Homologues
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    UniProt
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    Internet
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