Drosophila melanogasterGenAge entry for Gnmt (Drosophila melanogaster)

Gene information (ID: 2096)

Symbol
Gnmt
Name
Glycine N-methyltransferase
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Gnmt acts to buffer systemic S-adenosyl-methionine (SAM) synthesis. Overexpression of Gnmt resulted in an increase in lifespan, dependant on increased Gnmt enzymatic activity.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    CellAge
    • A homolog of this gene for Homo sapiens is present as GNMT

    Homologs in other organisms

    Danio rerio
    gnmt
    Homo sapiens
    GNMT
    Mus musculus
    Gnmt
    Rattus norvegicus
    LOC100911564
    Rattus norvegicus
    Gnmt

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (41561)
    Homologues
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    UniProt
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    Internet
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