- Symbol
- G6PD
- Name
- glucose-6-phosphate dehydrogenase
- Organism
- Mus musculus (AnAge)
- Observations
- Female mice overexpressing human G6PD (G6PD-Tg) had a 13.7% increase in median lifespan compared to wild type mice. G6PD-Tg mice had lower levels of oxidative stress and increased protection from age-associated functional decline. However, male mice showed no increase in median lifespan and neither male or female mice showed any increase in maximal lifespan.
- % change in avg or median lifespan
- Median lifespan is 14% higher in females.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Drosophila melanogaster is present as Zw
- A homolog of this gene for Saccharomyces cerevisiae is present as ZWF1
- GenAge microarray genes
- A homolog of this gene for Homo sapiens is present as G6PD
- LongevityMap
- A homolog of this gene for Homo sapiens is present as G6PD
- CellAge
- A homolog of this gene for Homo sapiens is present as G6PD
- Homo sapiens
- G6PD
- Homo sapiens
- G6PD
- Homo sapiens
- G6PD
- Homo sapiens
- G6PD
- Homo sapiens
- G6PD
- Homo sapiens
- G6PD
- Homo sapiens
- G6PD
- Homo sapiens
- G6PD
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (2539)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for G6PD (Mus musculus)