- Symbol
- Eip71CD
- Aliases
- CG7266; Dmel\CG7266; dmsrA; DROZ60MEX; Eip28; Eip28; /29
- Name
- Ecdysone-induced protein 28/29kD
- Organism
- Drosophila melanogaster (AnAge)
- Known functions and activities
- MSRA repairs damage resulting from oxidative stress
- Observations
- Overexpression in the nervous system extended lifespan by up to 70%, increased resistance to oxidative stress, and delayed the onset of senescence-induced decline in activity levels and reproductive capacity.
- % change in avg or median lifespan
- Lifespan is up to 70% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- Mean and maximal lifepsan was increased by up to 20% in flies with overexpressed Msra.
- % change in max lifespan
- Maximum lifespan is up to 20% higher.
- % change in avg or median lifespan
- Average lifespan is up to 20% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Mus musculus is present as Msra
- A homolog of this gene for Saccharomyces cerevisiae is present as MXR1
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as MSRA
- Caenorhabditis elegans
- msra-1
- Danio rerio
- msra
- Danio rerio
- si:ch1073-358c10.1
- Homo sapiens
- MSRA
- Mus musculus
- Msra
- Rattus norvegicus
- Msra
- Saccharomyces cerevisiae
- MXR1
- Schizosaccharomyces pombe
- mxr1
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (39675)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar