- Symbol
- Efemp1
- Name
- Epidermal growth factor-containing fibulin-like extracellular matrix protein 1
- Organism
- Mus musculus (AnAge)
- Known functions and activities
- Extracellular matrix (ECM) protein of unknown function
- Observations
- Knockout mice exhibited an early onset of ageing-associated phenotypes including a 20% shorted median lifespan and 30% shorter maximum lifespan, decreased body mass, lordokyphosis, reduced hair growth, and atrophy.
- % change in max lifespan
- Maximum lifespan is 30% lower.
- % change in avg or median lifespan
- Median lifespan is 20% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Knockout
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as EFEMP1
- GenAge microarray genes
- A homolog of this gene for Homo sapiens is present as EFEMP1
- CellAge gene expression
- A homolog of this gene for Homo sapiens is present as EFEMP1
- Caenorhabditis elegans
- fbl-1
- Danio rerio
- EFEMP1 (1 of many)
- Danio rerio
- EFEMP1 (1 of many)
- Drosophila melanogaster
- CG31999
- Homo sapiens
- EFEMP1
- Rattus norvegicus
- Efemp1
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (216616)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Efemp1 (Mus musculus)