- Symbol
- EUG1
- Name
- ER protein Unnecessary for Growth
- Organism
- Saccharomyces cerevisiae (AnAge)
- Observations
- Deletion of eug1, a target of the unfolded protein response signaling, increases replicative lifespan.
- % change in avg or median lifespan
- Mean lifespan is 11% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- Mean chronological lifespan decreased in the a strain
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Deletion
- Longevity Category
- Necessary for fitness
- Primary reference
-
- GenDR gene expression
- A homolog of this gene for Mus musculus is present as Pdia3
- Caenorhabditis elegans
- pdi-3
- Caenorhabditis elegans
- ZK973.11
- Caenorhabditis elegans
- pdi-2
- Caenorhabditis elegans
- pdi-1
- Caenorhabditis elegans
- C14B9.2
- Caenorhabditis elegans
- C06A6.5
- Caenorhabditis elegans
- C30H7.2
- Caenorhabditis elegans
- F42G8.7
- Danio rerio
- CABZ01108998.1
- Danio rerio
- erp44
- Danio rerio
- tmx3
- Danio rerio
- pdia4
- Danio rerio
- zgc:136472
- Danio rerio
- zgc:100906
- Danio rerio
- p4hb
- Danio rerio
- pdia2
- Danio rerio
- zgc:77086
- Danio rerio
- pdia3
- Drosophila melanogaster
- ERp60
- Drosophila melanogaster
- CG9911
- Drosophila melanogaster
- Pdi
- Drosophila melanogaster
- CG5027
- Drosophila melanogaster
- CG10029
- Homo sapiens
- PDILT
- Homo sapiens
- ERP27
- Homo sapiens
- PDIA4
- Homo sapiens
- PDIA2
- Homo sapiens
- TMX3
- Homo sapiens
- P4HB
- Homo sapiens
- PDIA3
- Homo sapiens
- ERP44
- Mus musculus
- Pdia3
- Mus musculus
- P4hb
- Mus musculus
- Pdia4
- Mus musculus
- Tmx3
- Mus musculus
- Erp44
- Mus musculus
- Pdilt
- Mus musculus
- Pdia2
- Mus musculus
- Erp27
- Rattus norvegicus
- Erp44
- Rattus norvegicus
- Pdilt
- Rattus norvegicus
- Pdia4
- Rattus norvegicus
- Erp27
- Rattus norvegicus
- Tmx3
- Rattus norvegicus
- P4hb
- Rattus norvegicus
- Pdia3
- Schizosaccharomyces pombe
- SPAC1F5.02
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (852130)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar