Drosophila melanogasterGenAge entry for Cat (Drosophila melanogaster)

Gene information (ID: 91)

Symbol
Cat
Aliases
bs36h11.y1; cat; CAT; CatA; CATA; CG6871; CT21282; DMCATH
Name
Catalase
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Protects cells from hydrogen peroxide

Potential relevance to longevity and/or ageing

Observations
Overexpression of catalase and Sod1 result in a one-third lifespan extension, a slower rate of mortality acceleration, and a delayed loss in physical performance.
% change in avg or median lifespan
Lifespan is one-third higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Mus musculus is present as Cat
    • A homolog of this gene for Saccharomyces cerevisiae is present as CTA1
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as CAT
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as CAT

    Homologs in other organisms

    Caenorhabditis elegans
    ctl-3
    Caenorhabditis elegans
    ctl-1
    Caenorhabditis elegans
    ctl-2
    Danio rerio
    cat
    Homo sapiens
    CAT
    Mus musculus
    Cat
    Rattus norvegicus
    Cat
    Saccharomyces cerevisiae
    CTA1

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (40048)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar