Drosophila melanogasterGenAge entry for CG5389 (Drosophila melanogaster)

Gene information (ID: 840)

Symbol
CG5389
Aliases
Dmel\CG5389
Name
CG5389 gene product from transcript CG5389-RA
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNAi started from the development resulted in a mild increase in lifespan in both sexes (3-11% in females, and 3-8% in males). Post-developmental RNAi and experiments limited to neurons had variable effects with reductions in lifespan of up to 9%.
% change in avg or median lifespan
Average female lifespan is up to 11% higher; Average male lifespan is up to 8% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as ATP2
    GenDR gene manipulations

    Homologs in other organisms

    Saccharomyces cerevisiae
    ATP2

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (39761)
    Homologues
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    UniProt
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    Internet
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