Drosophila melanogasterGenAge entry for Aut1 (Drosophila melanogaster)

Gene information (ID: 835)

Symbol
Aut1
Aliases
atg3; Atg3; CG6877; Dmel\CG6877; Draut1
Name
Aut1 -CG6877 gene product from transcript CG6877-RA
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Depletion of Atg3 from the first day of imaginal stage shortens life span in Drosophila and causes morphological and behavioral features of premature aging.
% change in avg or median lifespan
Average lifespan is 28% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as atg-3

    Homologs in other organisms

    Caenorhabditis elegans
    atg-3
    Danio rerio
    atg3
    Homo sapiens
    ATG3
    Mus musculus
    Atg3
    Rattus norvegicus
    Atg3
    Saccharomyces cerevisiae
    ATG3
    Schizosaccharomyces pombe
    atg3

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (40044)
    Homologues
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    UniProt
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    Internet
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