Drosophila melanogasterGenAge entry for Atg1 (Drosophila melanogaster)

Gene information (ID: 1908)

Symbol
Atg1
Name
Autophagy-specific gene 1
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Adult-onset, neuronal-specific upregulation of Atg1 results in increased median and maximum lifespan in female flies.
% change in avg or median lifespan
Median lifespan is up to 25% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as unc-51
    • A homolog of this gene for Saccharomyces cerevisiae is present as ATG1
    GenDR gene manipulations
    • A homolog of this gene for Caenorhabditis elegans is present as unc-51
    • A homolog of this gene for Saccharomyces cerevisiae is present as ATG1
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as ULK1

    Homologs in other organisms

    Caenorhabditis elegans
    unc-51
    Danio rerio
    ulk1a
    Danio rerio
    ulk2
    Danio rerio
    ulk1b
    Homo sapiens
    ULK2
    Homo sapiens
    ULK1
    Mus musculus
    Ulk1
    Mus musculus
    Ulk2
    Rattus norvegicus
    Ulk1
    Rattus norvegicus
    Ulk2
    Saccharomyces cerevisiae
    ATG1
    Schizosaccharomyces pombe
    atg1

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (39454)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar