Mus musculusGenAge entry for Akt2 (Mus musculus)

Gene information (ID: 2231)

Symbol
Akt2
Name
thymoma viral proto-oncogene 2
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Akt2-/- mice exhibited a 9.1% increase in mean lifespan. Median survival was 33 months for wild type mice and 36 months for Akt2-/- mice. However, the Akt2-/- mice showed increased cardiac hypertrophy.
% change in avg or median lifespan
Mean lifespan is 9% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as akt-1
    • A homolog of this gene for Saccharomyces cerevisiae is present as SCH9
    • A homolog of this gene for Drosophila melanogaster is present as Akt1
    • A homolog of this gene for Saccharomyces cerevisiae is present as YPK1
    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as SCH9

    Homologs in other organisms

    Caenorhabditis elegans
    akt-2
    Caenorhabditis elegans
    akt-1
    Danio rerio
    akt2
    Danio rerio
    akt2l
    Drosophila melanogaster
    Akt1
    Homo sapiens
    AKT2
    Rattus norvegicus
    Akt2
    Saccharomyces cerevisiae
    SCH9
    Saccharomyces cerevisiae
    YPK1
    Saccharomyces cerevisiae
    YPK2

    External links

    Mouse Genome Informatics
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (11652)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar