- Symbol
- Adra1a
- Name
- adrenergic receptor, alpha 1a
- Organism
- Mus musculus (AnAge)
- Observations
- Transgenic mice overexpressing a CAM form of the adrenergic receptor, alpha 1a (Adra1a), display an extended lifespan. Median lifespan taken for both sexes together is 10% higher than that of WT mice. While median lifespan increases for both sexes, this is significant for males only. Maximum lifespan also increases by 8% compared with WT mice.
- % change in max lifespan
- Maximum lifespan is 8% higher.
- % change in avg or median lifespan
- Median is 10% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Caenorhabditis elegans
- dop-4
- Danio rerio
- adra1ab
- Danio rerio
- adra1aa
- Drosophila melanogaster
- Dop1R2
- Homo sapiens
- ADRA1A
- Rattus norvegicus
- Adra1a
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (11549)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Adra1a (Mus musculus)