GenDR Dietary Restriction Gene Manipulation: RPD3
Gene Information (Entrez Gene ID: 855386)
- Symbol
- RPD3
- Aliases
- MOF6 REC3 SDI2 SDS6
- Name
- Reduced Potassium Dependency 3
- Organism
- Saccharomyces cerevisiae (AnAge)
- Entrez Gene ID
- 855386
Potential relevance to dietary restriction and ageing
- Observations
-
Deletion of the histone deacetylase gene RPD3 extends lifespan by 41%, independently of an intact Sir silencing complex (in the short-lived YSK661 strain) [203]. Deletion of RPD3 extends replicative lifespan and there was no additive effect by neither 0.1% glucose nor amino acid restriction [2552].
- References
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In other databases
- GenAge model organism genes
- GenAge human genes
- GenDR gene manipulations
- A homolog of this gene for Drosophila melanogaster is present as Rpd3
- CellAge
Homologs
- Caenorhabditis elegans
- hda-3
- Caenorhabditis elegans
- hda-1
- Danio rerio
- hdac1
- Danio rerio
- hdac3
- Danio rerio
- hdac8
- Drosophila melanogaster
- Hdac3
- Drosophila melanogaster
- Rpd3
- Homo sapiens
- HDAC2
- Homo sapiens
- HDAC3
- Homo sapiens
- HDAC8
- Homo sapiens
- HDAC1
- Mus musculus
- Hdac1
- Mus musculus
- Hdac8
- Mus musculus
- Hdac2
- Mus musculus
- Hdac3
- Mus musculus
- Gm10093
- Rattus norvegicus
- Hdac1l
- Rattus norvegicus
- Hdac1
- Rattus norvegicus
- Hdac8
- Rattus norvegicus
- Hdac2
- Rattus norvegicus
- Hdac3
- Schizosaccharomyces pombe
- clr6
External links
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- ID 855386
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar