Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: RIM15

Gene Information (Entrez Gene ID: 850511)

Symbol
RIM15
Aliases
TAK1
Name
Regulator of IME2 15
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
850511

Potential relevance to dietary restriction and ageing

Observations

RIM15 deletion results in 50% reduction of maximal chronological lifespan [2346] and consistently decreases chronological lifespan under ad libitum [2591]. Rim15 is required for chronological lifespan extension caused by deficiency in TOR1 or SCH9, as well as by 0.5% glucose restriction, but not by water starvation [2556].

References

    In other databases

    GenAge model organism genes
    • This gene is present as RIM15
    CellAge
    • A homolog of this gene for Homo sapiens is present as MAST1
    CellAge gene expression
    • A homolog of this gene for Homo sapiens is present as MAST3
    • A homolog of this gene for Homo sapiens is present as MASTL

    Homologs

    Caenorhabditis elegans
    kin-4
    Danio rerio
    mast1b
    Danio rerio
    mastl
    Danio rerio
    MAST3 (1 of many)
    Danio rerio
    mast1a
    Danio rerio
    mast2
    Danio rerio
    mast3b
    Drosophila melanogaster
    gwl
    Drosophila melanogaster
    dop
    Homo sapiens
    MAST3
    Homo sapiens
    MAST1
    Homo sapiens
    MAST2
    Homo sapiens
    MASTL
    Homo sapiens
    MAST4
    Mus musculus
    Mast3
    Mus musculus
    Mast4
    Mus musculus
    Mastl
    Mus musculus
    Mast1
    Mus musculus
    Mast2
    Rattus norvegicus
    NEWGENE_1310139
    Rattus norvegicus
    NEWGENE_1310139
    Rattus norvegicus
    Mastl
    Rattus norvegicus
    Mast3
    Rattus norvegicus
    MAST1
    Rattus norvegicus
    Mast4
    Rattus norvegicus
    Mast2
    Schizosaccharomyces pombe
    cek1

    External links

    Saccharomyces Genome Database
    Search
    Ensembl
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    Entrez Gene
    ID 850511
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar