Cell Senescence Entries for ZDHHC3
- Cell Types
- Breast cancer
- Cell Lines
- MCF-7, MDA-MB-231
- Cancer Cell?
- Yes
- Method
- Knockdown
- Type of senescence
- Stress-induced
- Senescence Effect
- Inhibits
- Primary Reference
- Sharma et al. (2018) Protein Acyltransferase DHHC3 Regulates Breast Tumor Growth, Oxidative Stress, and Senescence. Cancer Res 77(24)6880-6890 (PubMed)
ZDHHC3 Gene Information
- HGNC symbol
- ZDHHC3
- Aliases
- DHHC3; GODZ; ZNF373
- Common name
- zinc finger DHHC-type palmitoyltransferase 3
- Entrez Id
- 51304
- Description
ZDHHC3 Ontologies
- Gene Ontology
-
Process: GO:6612; protein targeting to membrane
GO:36462; TRAIL-activated apoptotic signaling pathway
GO:8277; regulation of G protein-coupled receptor signaling pathway
GO:72659; protein localization to plasma membrane
GO:1902685; positive regulation of receptor localization to synapse
GO:18230; peptidyl-L-cysteine S-palmitoylation
GO:18345; protein palmitoylation
GO:32230; positive regulation of synaptic transmission, GABAergic
GO:44873; lipoprotein localization to membrane
GO:1903546; protein localization to photoreceptor outer segment
Cellular component: GO:16020; membrane
GO:16021; integral component of membrane
GO:5794; Golgi apparatus
GO:139; Golgi membrane
GO:5783; endoplasmic reticulum
Show all GO termsFunction: GO:16740; transferase activity
GO:16746; acyltransferase activity
GO:16409; palmitoyltransferase activity
GO:19706; protein-cysteine S-palmitoyltransferase activity
GO:42803; protein homodimerization activity
GO:140439; protein-cysteine S-stearoyltransferase activity
GO:19705; protein-cysteine S-myristoyltransferase activity
Homologs of ZDHHC3 in Model Organisms
- Caenorhabditis elegans
- dhhc-3
- Danio rerio
- zdhhc3a
- Drosophila melanogaster
- CG8314
- Mus musculus
- Zdhhc3
- Rattus norvegicus
- Zdhhc3
- Saccharomyces cerevisiae
- PFA3
In other databases
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as PFA3
External links
- OMIM
- 617150
- Ensembl
- ENSG00000163812
- Entrez Gene
- 51304
- UniGene
- 61430
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- ZDHHC3
- GeneCards
- ZDHHC3