Cell Senescence Entries for MCAM

Cell Types
Umbilical cord blood-derived mesenchymal stem
Cell Lines
HUCB
Cancer Cell?
No
Method
Knockdown
Type of senescence
Replicative
Senescence Effect
Inhibits
Primary Reference
Jin et al. (2016) Downregulation of Melanoma Cell Adhesion Molecule (MCAM/CD146) Accelerates Cellular Senescence in Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells. Stem Cells Transl Med 5(4)427-39 (PubMed)

MCAM Gene Information

HGNC symbol
MCAM 
Aliases
CD146; HEMCAM; MelCAM; METCAM; MUC18 
Common name
melanoma cell adhesion molecule 
Entrez Id
4162
Description

MCAM Ontologies

Gene Ontology
Process: GO:7155; cell adhesion
GO:30335; positive regulation of cell migration
GO:9653; anatomical structure morphogenesis
GO:1525; angiogenesis
GO:3094; glomerular filtration
GO:61042; vascular wound healing
Cellular component: GO:16020; membrane
GO:16021; integral component of membrane
GO:5925; focal adhesion
GO:5615; extracellular space
GO:5634; nucleus
GO:5886; plasma membrane
GO:9897; external side of plasma membrane
GO:5576; extracellular region
Function:
Show all GO terms

Homologs of MCAM in Model Organisms

Danio rerio
mcama
Danio rerio
mcamb
Mus musculus
Mcam
Rattus norvegicus
Mcam

In other databases

LongevityMap
  • This gene is present as MCAM

External links

OMIM
155735
Ensembl
ENSG00000076706
Entrez Gene
4162
UniGene
599039
1000 Genomes
1000 Genomes
HPRD
GenAtlas
MCAM
GeneCards
MCAM