Cell Senescence Entries for MCAM
- Cell Types
- Umbilical cord blood-derived mesenchymal stem
- Cell Lines
- HUCB
- Cancer Cell?
- No
- Method
- Knockdown
- Type of senescence
- Replicative
- Senescence Effect
- Inhibits
- Primary Reference
- Jin et al. (2016) Downregulation of Melanoma Cell Adhesion Molecule (MCAM/CD146) Accelerates Cellular Senescence in Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells. Stem Cells Transl Med 5(4)427-39 (PubMed)
MCAM Gene Information
- HGNC symbol
- MCAM
- Aliases
- CD146; HEMCAM; MelCAM; METCAM; MUC18
- Common name
- melanoma cell adhesion molecule
- Entrez Id
- 4162
- Description
MCAM Ontologies
- Gene Ontology
-
Process: GO:7155; cell adhesion
GO:30335; positive regulation of cell migration
GO:9653; anatomical structure morphogenesis
GO:1525; angiogenesis
GO:3094; glomerular filtration
GO:61042; vascular wound healing
Cellular component: GO:16020; membrane
GO:16021; integral component of membrane
GO:5925; focal adhesion
GO:5615; extracellular space
GO:5634; nucleus
GO:5886; plasma membrane
GO:9897; external side of plasma membrane
GO:5576; extracellular region
Function:
Homologs of MCAM in Model Organisms
In other databases
- LongevityMap
- This gene is present as MCAM
External links
- OMIM
- 155735
- Ensembl
- ENSG00000076706
- Entrez Gene
- 4162
- UniGene
- 599039
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- MCAM
- GeneCards
- MCAM