Cell Senescence Entries for CDK18

Cell Types
Embryonic kidney, Lung fibroblast
Cell Lines
HEK293T, IMR-90, MRC-5
Cancer Cell?
No
Method
Overexpression
Type of senescence
Unclear
Senescence Effect
Induces
Primary Reference
Ferrand et al. (2016) Screening of a kinase library reveals novel pro-senescence kinases and their common NF-κB-dependent transcriptional program. Aging (Albany NY) 7(11)986-1003 (PubMed)

CDK18 Gene Information

HGNC symbol
CDK18 
Aliases
PCTAIRE3; PCTK3 
Common name
cyclin dependent kinase 18 
Entrez Id
5129
Description

CDK18 Ontologies

Gene Ontology
Process: GO:6468; protein phosphorylation
GO:16310; phosphorylation
GO:51726; regulation of cell cycle
GO:83; regulation of transcription involved in G1/S transition of mitotic cell cycle
Cellular component: GO:5634; nucleus
GO:5737; cytoplasm
GO:5575; cellular_component
Function: GO:166; nucleotide binding
GO:4672; protein kinase activity
GO:4674; protein serine/threonine kinase activity
GO:4712; protein serine/threonine/tyrosine kinase activity
GO:5524; ATP binding
GO:16301; kinase activity
GO:16740; transferase activity
GO:106310; protein serine kinase activity
GO:5515; protein binding
GO:4693; cyclin-dependent protein serine/threonine kinase activity
Show all GO terms

Homologs of CDK18 in Model Organisms

Caenorhabditis elegans
pct-1
Danio rerio
CDK18
Mus musculus
Cdk18
Rattus norvegicus
Cdk18
Saccharomyces cerevisiae
PHO85

In other databases

GenAge model organism genes
  • A homolog of this gene for Saccharomyces cerevisiae is present as PHO85

External links

OMIM
169190
Ensembl
ENSG00000117266
Entrez Gene
5129
UniGene
445402
1000 Genomes
1000 Genomes
HPRD
GenAtlas
CDK18
GeneCards
CDK18