LongevityMap Gene
Gene details
- HGNC symbol
- PRR5L
- Aliases
- PROTOR2
- Common name
- proline rich 5 like
- Description
- Cytogenetic Location
- 11p13-p12
- UCSC Genome Browser
- View 11p13-p12 on the UCSC genome browser
- OMIM
- 611728
- Ensembl
- ENSG00000135362
- UniProt/Swiss-Prot
- B3KNU3_HUMAN
- Entrez Gene
- 79899
- UniGene
- 19987
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Danio rerio
- si:dkey-56p7.10
- Danio rerio
- PRR5L
- Mus musculus
- Prr5l
- Rattus norvegicus
- Prr5l
Studies (1)
Significant/Non-significant: 1/0
- Longevity Association
- Significant
- Population
- Dutch
- Study Design
- 1,018 SNPs within a 10-kb window around 40 mTOR signalling genes were studied for differences in variation between 417 unrelated nonagenarian participants and 476 younger controls
- Conclusions
- As a whole, there was a significant association of genetic variation in the mTOR pathway and familial longevity, though no individual gene was significant after correcting for multiple hypothesis testing
- Indentifier
- PRR5L
- Reference