LongevityMap Gene
Gene details
- HGNC symbol
- DEPTOR
- Aliases
- DEP.6; DEPDC6
- Common name
- DEP domain containing MTOR interacting protein
- Description
- Cytogenetic Location
- 8q24.12
- UCSC Genome Browser
- View 8q24.12 on the UCSC genome browser
- OMIM
- 612974
- Ensembl
- ENSG00000155792
- UniProt/Swiss-Prot
- DPTOR_HUMAN
- Entrez Gene
- 64798
- UniGene
- 112981
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Danio rerio
- DEPTOR (1 of many)
- Danio rerio
- deptor
- Mus musculus
- Deptor
- Rattus norvegicus
- Deptor
In other databases
- CellAge
- This gene is present as DEPTOR
Studies (1)
Significant/Non-significant: 1/0
- Longevity Association
- Significant
- Population
- Dutch
- Study Design
- 1,018 SNPs within a 10-kb window around 40 mTOR signalling genes were studied for differences in variation between 417 unrelated nonagenarian participants and 476 younger controls
- Conclusions
- As a whole, there was a significant association of genetic variation in the mTOR pathway and familial longevity, though no individual gene was significant after correcting for multiple hypothesis testing
- Indentifier
- DEPTOR
- Reference