LongevityMap Gene
Gene details
- HGNC symbol
- C7orf50
- Aliases
- YCR016W
- Common name
- chromosome 7 open reading frame 50
- Description
- Cytogenetic Location
- 7p22.3
- UCSC Genome Browser
- View 7p22.3 on the UCSC genome browser
- OMIM
- Ensembl
- ENSG00000146540
- UniProt/Swiss-Prot
- CG050_HUMAN
- Entrez Gene
- 84310
- UniGene
- 653258
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Danio rerio
- 567594
- Mus musculus
- 3110082I17Rik
- Rattus norvegicus
- LOC498154
Studies (1)
Significant/Non-significant: 1/0
- Longevity Association
- Significant
- Population
- American (Caucasian)
- Study Design
- Genome-wide association study using 1,471 genotyped participants from the Framingham Heart Study, of which 1,173 individuals had known lifespans, plus 517 individuals from the Offspring cohort for validating connections between longevity and genetic variants
- Conclusions
- A total of 27 SNPs, including in CDH4, SVEP1, CACNA1C, CARS, STK24, C7orf50, PARVG, NCAM2, PPP2R2C, NLRC5, BTBD9, RAC2, TGFA, KIAA0649, ABCC4, CLSTN2, FAM19A5 and RUNX3, were identified at the intersection of various statistical procedures
- Indentifier
- rs10256972
- Reference