LongevityMap Gene
Gene details
- HGNC symbol
- ATG101
- Aliases
- C12orf44
- Common name
- autophagy related 101
- Description
- Cytogenetic Location
- 12q13.13
- UCSC Genome Browser
- View 12q13.13 on the UCSC genome browser
- OMIM
- 615089
- Ensembl
- ENSG00000123395
- UniProt/Swiss-Prot
- A0A024R128_HUMAN
- Entrez Gene
- 60673
- UniGene
- 9911
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Caenorhabditis elegans
- epg-9
- Danio rerio
- atg101
- Drosophila melanogaster
- Atg101
- Mus musculus
- Atg101
- Rattus norvegicus
- Atg101
- Schizosaccharomyces pombe
- mug66
Studies (1)
Significant/Non-significant: 1/0
- Longevity Association
- Significant
- Population
- Dutch
- Study Design
- 1,018 SNPs within a 10-kb window around 40 mTOR signalling genes were studied for differences in variation between 417 unrelated nonagenarian participants and 476 younger controls
- Conclusions
- As a whole, there was a significant association of genetic variation in the mTOR pathway and familial longevity, though no individual gene was significant after correcting for multiple hypothesis testing
- Indentifier
- C12orf44
- Reference