LongevityMap variant
Entry Details
- Longevity Association
- Non-significant
- Population
- Danish
- Study Design
- L/P33 SNP was examined in 187 Danish centenarians and 201 healthy controls aged 20-64 years (mean age 42 years)
- Conclusions
- No significant association with longevity was found
- Identifier
- 33L/P
- Cytogenetic Location
- 17q21.32
- UCSC Genome Browser
- View 17q21.32 on the UCSC genome browser
Gene details
- HGNC symbol
- ITGB3
- Aliases
- GT; CD61; GP3A; BDPLT2; GPIIIa; BDPLT16
- Common name
- integrin subunit beta 3
- Description
- The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
- Other longevity studies of this gene
- 1
- OMIM
- 173470
- Ensembl
- ENSG00000259207
- UniProt/Swiss-Prot
- ITB3_HUMAN
- Entrez Gene
- 3690
- UniGene
- 218040
- HapMap
- View on HapMap
Homologs in model organisms
In other databases
- CellAge
- This gene is present as ITGB3