LongevityMap variant
Entry Details
- Longevity Association
- Non-significant
- Population
- Danish
- Study Design
- The T/C (2437 coding) polymorphism was examined in a cohort of aged Danish twins (individuals aged between 70 and 91 years, categorized according to the presence or absence of various diseases)
- Conclusions
- No association with longevity was found
- Identifier
- 2437T/C
- Cytogenetic Location
- 6p21.33
- UCSC Genome Browser
- View 6p21.33 on the UCSC genome browser
Gene details
- HGNC symbol
- HSPA1L
- Aliases
- HSP70T; hum70t; HSP70-1L; HSP70-HOM
- Common name
- heat shock protein family A (Hsp70) member 1 like
- Description
- This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq, Jul 2008]
- Other longevity studies of this gene
- 8
- OMIM
- 140559
- Ensembl
- ENSG00000204390
- UniProt/Swiss-Prot
- HS71L_HUMAN
- Entrez Gene
- 3305
- UniGene
- 690634
- HapMap
- View on HapMap