LongevityMap variant
Entry Details
- Longevity Association
- Significant
- Population
- American (Caucasian)
- Study Design
- Genome-wide association study using 1,471 genotyped participants from the Framingham Heart Study, of which 1,173 individuals had known lifespans, plus 517 individuals from the Offspring cohort for validating connections between longevity and genetic variants
- Conclusions
- A total of 27 SNPs, including in CDH4, SVEP1, CACNA1C, CARS, STK24, C7orf50, PARVG, NCAM2, PPP2R2C, NLRC5, BTBD9, RAC2, TGFA, KIAA0649, ABCC4, CLSTN2, FAM19A5 and RUNX3, were identified at the intersection of various statistical procedures
- Identifier
- rs139170
- Cytogenetic Location
- 22q13.31
- UCSC Genome Browser
- View 22q13.31 on the UCSC genome browser
Gene details
- HGNC symbol
- PARVG
- Aliases
- Common name
- parvin gamma
- Description
- Members of the parvin family, including PARVG, are actin-binding proteins associated with focal contacts.[supplied by OMIM, Aug 2004]
- OMIM
- 608122
- Ensembl
- ENSG00000138964
- UniProt/Swiss-Prot
- A0A024R4U4_HUMAN
- Entrez Gene
- 64098
- UniGene
- 658995
- HapMap
- View on HapMap
Homologs in model organisms
- Caenorhabditis elegans
- pat-6
- Danio rerio
- parvg
- Drosophila melanogaster
- parvin
- Mus musculus
- Parvg
- Rattus norvegicus
- Parvg
In other databases
- GenAge model organism genes
- A homolog of this gene for Caenorhabditis elegans is present as pat-6