Drosophila melanogasterGenAge entry for Pten (Drosophila melanogaster)

Gene information (ID: 876)

Symbol
Pten
Aliases
CG5671; Dmel\CG5671; dpten; dPten; dPTEN; DPTEN; pten; PT
Name
CG5671 gene product from transcript CG5671-RB
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Lifespan of flies with increased Pten and 4E-BP activity in muscles is extended in comparison with matched controls.
% change in max lifespan
Maximum lifespan is 7.7% higher.
% change in avg or median lifespan
Median lifespan is 12.7% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as daf-18
    • A homolog of this gene for Mus musculus is present as Pten
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as PTEN
    CellAge
    • A homolog of this gene for Homo sapiens is present as PTEN

    Homologs in other organisms

    Caenorhabditis elegans
    daf-18
    Danio rerio
    ptena
    Danio rerio
    ptenb
    Homo sapiens
    PTEN
    Mus musculus
    Pten
    Rattus norvegicus
    Pten

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (43991)
    Homologues
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    UniProt
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    Internet
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