Caenorhabditis elegansGenAge entry for vrk-1 (Caenorhabditis elegans)

Gene information (ID: 721)

Symbol
vrk-1
Name
Vaccinia Related Kinase
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Signalling

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 36% in wild type animals, 54% in a daf-2 background and 12% in daf-2/daf-16 double mutants.
% change in avg or median lifespan
Median lifespan is 36% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    CellAge gene expression
    • A homolog of this gene for Homo sapiens is present as VRK1

    Homologs in other organisms

    Danio rerio
    vrk3
    Danio rerio
    vrk1
    Danio rerio
    vrk2
    Drosophila melanogaster
    ball
    Drosophila melanogaster
    CG8878
    Homo sapiens
    VRK1
    Homo sapiens
    VRK2
    Homo sapiens
    VRK3
    Mus musculus
    Vrk3
    Mus musculus
    Vrk1
    Mus musculus
    Vrk2
    Rattus norvegicus
    Vrk3
    Rattus norvegicus
    Vrk2
    Rattus norvegicus
    Vrk1
    Saccharomyces cerevisiae
    HRR25

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (174004)
    Homologues
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    UniProt
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    Internet
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