- Symbol
- myo
- Name
- myoglianin
- Organism
- Drosophila melanogaster (AnAge)
- Observations
- Similarly to Mnt, Myoglianin (myo) overexpression in flies lowers climbing defects and increases both median and maximum lifespan. Contrastly, RNAi against myoglianin shortens median lifespan and results in more age-related climbing defects.
- % change in max lifespan
- Maximum lifespan is aproximately 20% higher.
- % change in avg or median lifespan
- Median lifespan is aproximately 25% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Mus musculus is present as Mstn
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as GDF11
- LongevityMap
- A homolog of this gene for Homo sapiens is present as MSTN
- Danio rerio
- mstna
- Danio rerio
- mstnb
- Danio rerio
- gdf11
- Homo sapiens
- MSTN
- Homo sapiens
- GDF11
- Mus musculus
- Mstn
- Mus musculus
- Gdf11
- Rattus norvegicus
- Mstn
- Rattus norvegicus
- Gdf11
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (43811)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for myo (Drosophila melanogaster)