Drosophila melanogasterGenAge entry for let-7 (Drosophila melanogaster)

Gene information (ID: 2236)

Symbol
let-7
Name
let-7
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Ubiquitous overexpression of let-7 increased median lifespan by 8% in female fruit flies. Adult specific neuronal overexpression of let-7 increased median lifespan in females 22%. Ubiquitous and neuronal expression decreased lifespan in males.
Lifespan Effect
Not Recorded
Genetic Manipulation
Overexpression
Primary reference

    Homologs in other organisms

    No homologs found

    External links

    FlyBase
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    Entrez Gene
    View on Entrez Gene database (12798012)
    Homologues
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    Internet
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