Drosophila melanogasterGenAge entry for l(3)neo18 (Drosophila melanogaster)

Gene information (ID: 862)

Symbol
l(3)neo18
Aliases
CG9762; Dmel\CG9762
Name
l(3)neo18
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
In females, RNAi increased mean life span by 14-18% when done both during development and adulthood in the whole organism and by 8-24% when done in the neurons. In males, the effect is more variable. A consistent increase (8-18%) was however observed for whole organism RNAi, in adults.
% change in avg or median lifespan
Average female lifespan is up to 24% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge microarray genes
    • A homolog of this gene for Homo sapiens is present as NDUFB5
    GenDR gene manipulations

    Homologs in other organisms

    Danio rerio
    ndufb5
    Homo sapiens
    NDUFB5
    Mus musculus
    Ndufb5
    Rattus norvegicus
    Ndufb5

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (46260)
    Homologues
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    UniProt
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    Internet
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