- Symbol
- hop
- Aliases
- 4; CG1594; d-jak; Dm; JAK; Dmel\CG1594; DmHD-160; HD-160;
- Name
- hopscotch
- Organism
- Drosophila melanogaster (AnAge)
- Observations
- Flies heterozygous for the gain-of-function hopTum-l mutation exhibited shortened lifespans compared with wild-type control flies.
- % change in max lifespan
- Maximum lifespan is 10% lower.
- % change in avg or median lifespan
- Average lifespan is 30% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Mutation
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- Flies heterozygous for a loss-of-function hop allele, hop3, had longer lifespans.
- % change in max lifespan
- Maximum lifespan is 20% higher.
- % change in avg or median lifespan
- Average lifespan is 17% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Mutation
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as JAK2
- LongevityMap
- A homolog of this gene for Homo sapiens is present as JAK2
- CellAge
- A homolog of this gene for Homo sapiens is present as JAK2
- A homolog of this gene for Homo sapiens is present as TYK2
- Danio rerio
- jak2b
- Danio rerio
- jak3
- Danio rerio
- jak2a
- Danio rerio
- jak1
- Danio rerio
- tyk2
- Homo sapiens
- TYK2
- Homo sapiens
- JAK1
- Homo sapiens
- JAK2
- Homo sapiens
- JAK3
- Mus musculus
- Tyk2
- Mus musculus
- Jak3
- Mus musculus
- Jak1
- Mus musculus
- Jak2
- Rattus norvegicus
- Jak1
- Rattus norvegicus
- Tyk2
- Rattus norvegicus
- Jak2
- Rattus norvegicus
- Jak3
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (32080)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for hop (Drosophila melanogaster)