Drosophila melanogasterGenAge entry for dj-1beta (Drosophila melanogaster)

Gene information (ID: 179)

Symbol
dj-1beta
Aliases
CG1349; DJ-1; DJ-1b; DJ-1B; DJ-1beta; Dmel\CG1349
Name
dj-1beta
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Possibly involved in the pathogenesis of Parkinson disease

Potential relevance to longevity and/or ageing

Observations
Loss of function mutation shortened maximum lifespan by 40% and resulted in increased sensitivity to oxidative stress and motor impairments.
% change in max lifespan
Maximal lifespan is 40% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    No homologs found

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (43652)
    Homologues
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    UniProt
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    Internet
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