Drosophila melanogasterGenAge entry for daw (Drosophila melanogaster)

Gene information (ID: 1899)

Symbol
daw
Name
dawdle
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Post developmental RNA interference of Daw in the whole body increases lifespan by up to 35%. Tissue specific RNA interference also increases lifespan mildly (by ~11%) in muscle but not in adipose tissue (where it decreases lifespan).
% change in avg or median lifespan
Mean lifespan is 35.3% higher.
Lifespan Effect
Increase
Genetic Manipulation
Post developmental RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as TGFB1
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as TGFB1
    • A homolog of this gene for Homo sapiens is present as TGFB2
    CellAge
    • A homolog of this gene for Homo sapiens is present as TGFB2
    CellAge gene expression
    • A homolog of this gene for Homo sapiens is present as TGFB2

    Homologs in other organisms

    Danio rerio
    tgfb3
    Danio rerio
    tgfb1a
    Danio rerio
    tgfb2l
    Danio rerio
    tgfb1b
    Danio rerio
    tgfb2
    Homo sapiens
    TGFB2
    Homo sapiens
    TGFB3
    Homo sapiens
    TGFB1
    Mus musculus
    Tgfb3
    Mus musculus
    Tgfb1
    Mus musculus
    Tgfb2
    Rattus norvegicus
    Tgfb2
    Rattus norvegicus
    Tgfb3
    Rattus norvegicus
    Tgfb1

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (33474)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar