Drosophila melanogasterGenAge entry for bsk (Drosophila melanogaster)

Gene information (ID: 837)

Symbol
bsk
Aliases
Bsk; BSK; BSK/DJNK; c-Jun; CG5680; D-JNK; D-junk; DBSK/JN
Name
basket
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNA interference of Bsk in intestinal stem cells, results in mutants with impaired intestinal homeostasis and tissue regeneration and are short-lived.
% change in avg or median lifespan
Average male lifespan is 16.4% lower; Average female lifespan is 10.2% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as jnk-1
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as MAPK8
    • A homolog of this gene for Homo sapiens is present as MAPK9
    CellAge
    • A homolog of this gene for Homo sapiens is present as MAPK9

    Homologs in other organisms

    Caenorhabditis elegans
    jnk-1
    Danio rerio
    mapk8a
    Danio rerio
    mapk9
    Danio rerio
    mapk10
    Danio rerio
    mapk8b
    Homo sapiens
    MAPK10
    Homo sapiens
    MAPK8
    Homo sapiens
    MAPK9
    Mus musculus
    Mapk8
    Mus musculus
    Mapk10
    Mus musculus
    Mapk9
    Rattus norvegicus
    Mapk8
    Rattus norvegicus
    Mapk9
    Rattus norvegicus
    Mapk10
    Saccharomyces cerevisiae
    HOG1

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (44801)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar