Drosophila melanogasterGenAge entry for VhaSFD (Drosophila melanogaster)

Gene information (ID: 716)

Symbol
VhaSFD
Aliases
144191_at; ATP6V1H; CG17332; Dmel\CG17332; V-ATPase; vh
Name
Vacuolar H+-ATPase SFD subunit
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Regulatory subunit of the vacuolar ATPase proton pump

Potential relevance to longevity and/or ageing

Observations
Overexpression results in a 5-10% increase in mean lifespan.
% change in avg or median lifespan
Average lifespan is 5-10% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as VMA13

    Homologs in other organisms

    Caenorhabditis elegans
    vha-15
    Danio rerio
    atp6v1h
    Homo sapiens
    ATP6V1H
    Mus musculus
    Atp6v1h
    Rattus norvegicus
    Atp6v1h
    Saccharomyces cerevisiae
    VMA13
    Schizosaccharomyces pombe
    vma13

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (34997)
    Homologues
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    UniProt
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    Internet
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