- Symbol
- Hsp70Ba
- Aliases
- CG31449; dhsp70; dHsp70; Dm-hsp70; Dmel\CG31449; Hsp; 70
- Name
- Heat shock 70kDa protein 1A
- Organism
- Drosophila melanogaster (AnAge)
- Observations
- hsp70 and hsp22 RNA levels were higher in long-lived than in short-lived fly lines. The HDAC inhibitor TSA (causing a higher expression of hsp22
and hsp70) strikingly influenced the lifespan in both long and short-lived lines, with variable degrees (up to 25%).
- % change in max lifespan
- Maximum lifespan is up to 16% higher.
- % change in avg or median lifespan
- Average lifespan is up to 25% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Epigenetic modification
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- Reduced mean and maximal lifespan (up to 30%) when overexpressed.
- % change in max lifespan
- Maximum lifespan is 30% lower.
- % change in avg or median lifespan
- Average lifespan is 30% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Overexpression
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as SSA3
- Caenorhabditis elegans
- hsp-70
- Caenorhabditis elegans
- F44E5.5
- Caenorhabditis elegans
- F44E5.5
- Saccharomyces cerevisiae
- SSA3
- Saccharomyces cerevisiae
- SSA1
- Saccharomyces cerevisiae
- SSA3
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (44921)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Hsp70Ba (Drosophila melanogaster)