- Symbol
- Hex-C
- Name
- Hexokinase C
- Organism
- Drosophila melanogaster (AnAge)
- Observations
- A mutation that decreased Hex-C activity in flies increased lifespan by more than 6 days. When flies with mutant Hex-C were subjected to dietary restriction no further lifespan extension was displayed, lifespan was comparable to wild type flies under dietary restriction and flies with mutant Hex-C under normal conditions. Thus decreased Hex-C activity triggers a dietary restriction like effect.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Mutation
- Longevity Category
- Anti-Longevity
- Primary reference
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- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as HXK2
- A homolog of this gene for Saccharomyces cerevisiae is present as GLK1
- GenDR gene expression
- A homolog of this gene for Mus musculus is present as Gck
- GenDR gene manipulations
- This gene is present as Hex-C
- A homolog of this gene for Saccharomyces cerevisiae is present as HXK2
- CellAge
- A homolog of this gene for Homo sapiens is present as HK3
- Caenorhabditis elegans
- hxk-1
- Danio rerio
- gck
- Danio rerio
- hkdc1
- Danio rerio
- hk2
- Danio rerio
- hk1
- Homo sapiens
- HKDC1
- Homo sapiens
- HK2
- Homo sapiens
- GCK
- Homo sapiens
- HK1
- Homo sapiens
- HK3
- Mus musculus
- Hk2
- Mus musculus
- Hk3
- Mus musculus
- Hk1
- Mus musculus
- Gck
- Mus musculus
- Hkdc1
- Rattus norvegicus
- Hk3
- Rattus norvegicus
- Hk2
- Rattus norvegicus
- Hk1
- Rattus norvegicus
- LOC100364027
- Rattus norvegicus
- Gck
- Saccharomyces cerevisiae
- HXK2
- Saccharomyces cerevisiae
- GLK1
- Schizosaccharomyces pombe
- hxk1
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (44008)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Hex-C (Drosophila melanogaster)