Drosophila melanogasterGenAge entry for Ef1alpha48D (Drosophila melanogaster)

Gene information (ID: 208)

Symbol
Ef1alpha48D
Aliases
1275; anon-EST:Liang-1.17; anon-EST:Liang-2.46; CG828
Name
Elongation factor 148D
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Ef1alpha48D is involved in the binding of tRNA to ribosomes during protein synthesis

Potential relevance to longevity and/or ageing

Observations
Overexpression results in lifespan extension by 18%-41%.
% change in avg or median lifespan
Lifespan is 18-41% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as eef-1A.1

    Homologs in other organisms

    Caenorhabditis elegans
    eef-1A.2
    Caenorhabditis elegans
    eef-1A.1
    Danio rerio
    eef1a1l1
    Danio rerio
    eef1a2
    Danio rerio
    si:dkey-37o8.1
    Danio rerio
    eef1a1l1
    Saccharomyces cerevisiae
    TEF2
    Saccharomyces cerevisiae
    TEF2

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (36271)
    Homologues
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    UniProt
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    Internet
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