Drosophila melanogasterGenAge entry for Cdk5 (Drosophila melanogaster)

Gene information (ID: 108)

Symbol
Cdk5
Aliases
cdk5; CDK5; CG8203; DmCdk5; Dmel\CG8203
Name
Cyclin-dependent kinase 5
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Cell cycle

Potential relevance to longevity and/or ageing

Observations
Loss-of-function mutations result in defective axon guidance, age-dependent behavioral deficits and reduced lifespan by about one third.
% change in avg or median lifespan
Lifespan is about one-third lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    CellAge
    • A homolog of this gene for Homo sapiens is present as CDK5

    Homologs in other organisms

    Caenorhabditis elegans
    cdk-5
    Danio rerio
    cdk5
    Homo sapiens
    CDK5
    Mus musculus
    Cdk5
    Rattus norvegicus
    Cdk5
    Saccharomyces cerevisiae
    CDC28

    External links

    FlyBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (36727)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar