- Symbol
- Cbs
- Aliases
- CBS; CG1753; dCBS; Dmel\CG1753
- Name
- Cystathionine beta-synthase
- Organism
- Drosophila melanogaster (AnAge)
- Observations
- Adult-specific ubiquitous overexpression of dCBS increases female mean and maximum lifespan by 12 - 43% and 10%, respectively. Males exhibit a smaller, but still significant increase in lifespan by 7% upon dCBS overexpression. Neuronal overexpression also increases lifespan, albeit modestly (approximately 12% mean and 15% maximum lifespan extension), whereas overexpression in the fat body and in the gut has no effect.
- % change in avg or median lifespan
- Average lifespan is up to 43% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as CYS4
- GenDR gene manipulations
- This gene is present as Cbs
- CellAge
- A homolog of this gene for Homo sapiens is present as CBS
- CellAge gene expression
- A homolog of this gene for Homo sapiens is present as CBS
- Caenorhabditis elegans
- F59A7.7
- Caenorhabditis elegans
- cysl-3
- Caenorhabditis elegans
- cysl-1
- Caenorhabditis elegans
- cysl-4
- Caenorhabditis elegans
- cysl-2
- Danio rerio
- cbsa
- Danio rerio
- cbsb
- Homo sapiens
- CBSL
- Homo sapiens
- CBS
- Mus musculus
- Cbs
- Rattus norvegicus
- Cbs
- Saccharomyces cerevisiae
- CYS4
- Schizosaccharomyces pombe
- cys12
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (33081)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Cbs (Drosophila melanogaster)