- Symbol
- AhcyL1
- Name
- Adenosylhomocysteinase like 1
- Organism
- Drosophila melanogaster (AnAge)
- Observations
- Downregulation of two out of three of Drosophila homologs of AHCY significantly extended life span in adult males and females, median lifespan was 13% higher when CG9977 was downregulated. Brain and intestine specific downregulation of CG9977 resulted in increased lifespan and health span.
- % change in avg or median lifespan
- Median lifespan is 13% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
- CellAge gene expression
- A homolog of this gene for Homo sapiens is present as AHCYL2
- Danio rerio
- AHCYL2 (1 of many)
- Danio rerio
- ahcyl2
- Danio rerio
- ahcyl1
- Homo sapiens
- AHCYL2
- Homo sapiens
- AHCYL1
- Mus musculus
- Ahcyl1
- Mus musculus
- Ahcyl2
- Rattus norvegicus
- Ahcyl1
- Rattus norvegicus
- Ahcyl2
- Saccharomyces cerevisiae
- SAH1
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (38342)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for AhcyL1 (Drosophila melanogaster)